Critical infrastructure and industrial organizations depend on operational technology (OT) to execute, monitor, and control physical processes. In today’s threat environment, IT is needed to configure and manage OT devices and collect data about OT operations to ensure enterprise-wide cybersecurity. As organizations work to implement Zero Trust, the necessary intersection of IT and OT introduces complexity and opportunity. This cross-industry panel will discuss the organizational and technical changes required to implement Zero Trust across IT and OT and their challenges and successes along the way.